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Exhibit 12

McKinsey & Company’s blueprint to help engineer economic development and growth.

Exhibit 12: Comparison of pharmaceutical R&D spend and West Virginia disease profile [42]
West Virginia Disease Profile Pharmaceutical R&D spending by Therapeutic Area *%) WV Rank of Mortality Rate
(1-5), (6-50)
WVU Focus Area?
Anti-Cancer 23 1 Yes
Cardiovascular 19 2 Yes
Ailmentary & Metabolism 13 1
Musculoskeletal  12 9
Nervous System 10 6 Yes
Anti-Infectives 4 5
Other 20 1

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*Citations available upon request.